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Design, synthesis and biological evaluation of imidazopyridine–propenone conjugates as potent tubulin inhibitors
A library of imidazopyridine–propenone conjugates (8a–8u) were synthesized and evaluated for their antitumor activity against four human cancer cell lines, namely, prostate (DU-145), lung (A549), cervical (Hela) and breast (MCF-7) cancer cell lines. These conjugates showed good to moderate activity...
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| Publicat a: | Medchemcomm |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072242/ https://ncbi.nlm.nih.gov/pubmed/30108815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00043j |
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