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HIV-1 gp41 Residues Modulate CD4-Induced Conformational Changes in the Envelope Glycoprotein and Evolution of a Relaxed Conformation of gp120

Entry of human immunodeficiency virus type 1 (HIV-1) into host cells is mediated by conformational changes in the envelope glycoprotein (Env) that are triggered by Env binding to cellular CD4 and chemokine receptors. These conformational changes involve the opening of the gp120 surface subunit, expo...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Keller, Paul W., Morrison, Orrianne, Vassell, Russell, Weiss, Carol D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069199/
https://ncbi.nlm.nih.gov/pubmed/29875245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00583-18
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