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HIV-1 gp41 Residues Modulate CD4-Induced Conformational Changes in the Envelope Glycoprotein and Evolution of a Relaxed Conformation of gp120

Entry of human immunodeficiency virus type 1 (HIV-1) into host cells is mediated by conformational changes in the envelope glycoprotein (Env) that are triggered by Env binding to cellular CD4 and chemokine receptors. These conformational changes involve the opening of the gp120 surface subunit, expo...

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Vydáno v:J Virol
Hlavní autoři: Keller, Paul W., Morrison, Orrianne, Vassell, Russell, Weiss, Carol D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069199/
https://ncbi.nlm.nih.gov/pubmed/29875245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00583-18
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