RalA controls glucose homeostasis by regulating glucose uptake in brown fat

Insulin increases glucose uptake into adipose tissue and muscle by increasing trafficking of the glucose transporter Glut4. In cultured adipocytes, the exocytosis of Glut4 relies on activation of the small G protein RalA by insulin, via inhibition of its GTPase activating complex RalGAP. Here, we ev...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Skorobogatko, Yuliya, Dragan, Morgan, Cordon, Claudia, Reilly, Shannon M., Hung, Chao-Wei, Xia, Wenmin, Zhao, Peng, Wallace, Martina, Lackey, Denise E., Chen, Xiao-Wei, Osborn, Olivia, Bogner-Strauss, Juliane G., Theodorescu, Dan, Metallo, Christian M., Olefsky, Jerrold M., Saltiel, Alan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065037/
https://ncbi.nlm.nih.gov/pubmed/29915037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801050115
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