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A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes

Insulin-stimulated glucose uptake in fat and muscle is mediated by the major facilitative glucose transporter Glut4. Insulin controls the trafficking of Glut4 to the plasma membrane via regulation of a series of small G proteins, including RalA and Rab10. We demonstrate here that Rab10 is a bona fid...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Karunanithi, Sheelarani, Xiong, Tingting, Uhm, Maeran, Leto, Dara, Sun, Jingxia, Chen, Xiao-Wei, Saltiel, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230594/
https://ncbi.nlm.nih.gov/pubmed/25103239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1060
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