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A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

Insulin stimulates glucose transport in muscle  and adipose tissue by translocation of glucose transporter 4 (GLUT4) to the plasma membrane. We previously reported that activation of the small GTPase RalA downstream of PI 3-kinase plays a critical role in this process by mobilizing the exocyst compl...

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Detalhes bibliográficos
Main Authors: Chen, Xiao-Wei, Leto, Dara, Xiong, Tingting, Yu, Genggeng, Cheng, Alan, Decker, Stuart, Saltiel, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016972/
https://ncbi.nlm.nih.gov/pubmed/21148297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0665
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