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TD-60 links RalA GTPase function to the CPC in mitosis

TD-60 (also known as RCC2) is a highly conserved protein that structurally resembles the Ran guanine exchange factor (GEF) RCC1, but has not previously been shown to have GEF activity. TD-60 has a typical chromosomal passenger complex (CPC) distribution in mitotic cells, but associates with integrin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Papini, Diana, Langemeyer, Lars, Abad, Maria A., Kerr, Alastair, Samejima, Itaru, Eyers, Patrick A., Jeyaprakash, A. Arockia, Higgins, Jonathan M. G., Barr, Francis A., Earnshaw, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510650/
https://ncbi.nlm.nih.gov/pubmed/26158537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8678
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