RalA controls glucose homeostasis by regulating glucose uptake in brown fat

Insulin increases glucose uptake into adipose tissue and muscle by increasing trafficking of the glucose transporter Glut4. In cultured adipocytes, the exocytosis of Glut4 relies on activation of the small G protein RalA by insulin, via inhibition of its GTPase activating complex RalGAP. Here, we ev...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Skorobogatko, Yuliya, Dragan, Morgan, Cordon, Claudia, Reilly, Shannon M., Hung, Chao-Wei, Xia, Wenmin, Zhao, Peng, Wallace, Martina, Lackey, Denise E., Chen, Xiao-Wei, Osborn, Olivia, Bogner-Strauss, Juliane G., Theodorescu, Dan, Metallo, Christian M., Olefsky, Jerrold M., Saltiel, Alan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065037/
https://ncbi.nlm.nih.gov/pubmed/29915037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801050115
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