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Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts
Inhibition of mTOR signaling using rapamycin has been shown to increase lifespan and healthspan in multiple model organisms; however, the precise mechanisms for the beneficial effects of rapamycin remain uncertain. We have previously reported that rapamycin delays senescence in human cells and that...
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| Veröffentlicht in: | GeroScience |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6060207/ https://ncbi.nlm.nih.gov/pubmed/29931650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0030-2 |
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