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Metabolic Regulation of the Senescence Program

Cellular senescence is a cell fate defined by an irreversible cell-cycle arrest and a pro-inflammatory secretory profile. It is a consequence of a shift in metabolism and rearrangement of chromatin. Accumulation of senescent cells is a universal hallmark of age-related pathologies suggesting these c...

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Bibliographic Details
Published in:Innov Aging
Main Authors: Potnis, Manali, Nacarelli, Timothy, Noguchi, Eishi, Azar, Ashley, Sell, Christian
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740386/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.437
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