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Inhibition of mTOR prevents ROS production initiated by ethidium bromide-induced mitochondrial DNA depletion.
The regulation of mitochondrial mass and DNA content involves a complex interaction between mitochondrial DNA replication machinery, functional components of the electron transport chain, selective clearance of mitochondria, and nuclear gene expression. In order to gain insight into cellular respons...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2014-07-01
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| Col·lecció: | Frontiers in Endocrinology |
| Matèries: | |
| Accés en línia: | http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00122/full |
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