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In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells
On murine T cells, GPI-anchored ADP-ribosyltransferase 2.2 (ARTC2.2) ADP-ribosylates the P2X7 ion channel at arginine 125 in response to nicotinamide adenine dinucleotide (NAD(+)) released during cell preparation. We have previously shown that chronic gating of P2X7 by ADP-ribosylation reduces the v...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6046629/ https://ncbi.nlm.nih.gov/pubmed/30038627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01580 |
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