Interferon regulatory factor 4 controls effector functions of CD8(+) memory T cells

The transcription factor IRF4 is required for CD8(+) T cell activation, proliferation, and differentiation to effector cells and thus is essential for robust CD8(+) T cell responses. The function of IRF4 in memory CD8(+) T cells yet needs to be explored. To investigate the role of IRF4 for maintaini...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Harberts, Aenne, Schmidt, Constantin, Schmid, Joanna, Reimers, Daniel, Koch-Nolte, Friedrich, Mittrücker, Hans-Willi, Raczkowski, Friederike
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072204/
https://ncbi.nlm.nih.gov/pubmed/33859042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014553118
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