CD39 is upregulated during activation of mouse and human T cells and attenuates the immune response to Listeria monocytogenes

The ectoenzymes CD39 and CD73 degrade extracellular ATP to adenosine. ATP is released by stressed or damaged cells and provides pro-inflammatory signals to immune cells through P2 receptors. Adenosine, on the other hand, suppresses immune cells by stimulating P1 receptors. Thus, CD39 and CD73 can sh...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raczkowski, Friederike, Rissiek, Anne, Ricklefs, Isabell, Heiss, Kirsten, Schumacher, Valéa, Wundenberg, Kira, Haag, Friedrich, Koch-Nolte, Friedrich, Tolosa, Eva, Mittrücker, Hans-Willi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942830/
https://ncbi.nlm.nih.gov/pubmed/29742141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197151
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