CD39 is upregulated during activation of mouse and human T cells and attenuates the immune response to Listeria monocytogenes

The ectoenzymes CD39 and CD73 degrade extracellular ATP to adenosine. ATP is released by stressed or damaged cells and provides pro-inflammatory signals to immune cells through P2 receptors. Adenosine, on the other hand, suppresses immune cells by stimulating P1 receptors. Thus, CD39 and CD73 can sh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Raczkowski, Friederike, Rissiek, Anne, Ricklefs, Isabell, Heiss, Kirsten, Schumacher, Valéa, Wundenberg, Kira, Haag, Friedrich, Koch-Nolte, Friedrich, Tolosa, Eva, Mittrücker, Hans-Willi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942830/
https://ncbi.nlm.nih.gov/pubmed/29742141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197151
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