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Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq
Cycling cells duplicate their DNA content during S phase, following a defined program called replication timing (RT). Early and late replicating regions differ in terms of mutation rates, transcriptional activity, chromatin marks and sub-nuclear position. Moreover, RT is regulated during development...
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| 發表在: | Nat Protoc |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044726/ https://ncbi.nlm.nih.gov/pubmed/29599440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.148 |
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