Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq

Cycling cells duplicate their DNA content during S phase, following a defined program called replication timing (RT). Early and late replicating regions differ in terms of mutation rates, transcriptional activity, chromatin marks and sub-nuclear position. Moreover, RT is regulated during development...

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Bibliografiska uppgifter
I publikationen:Nat Protoc
Huvudupphovsmän: Marchal, Claire, Sasaki, Takayo, Vera, Daniel, Wilson, Korey, Sima, Jiao, Rivera-Mulia, Juan Carlos, Trevilla-García, Claudia, Nogues, Coralin, Nafie, Ebtesam, Gilbert, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044726/
https://ncbi.nlm.nih.gov/pubmed/29599440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.148
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