DNA replication timing alterations identify common markers between distinct progeroid diseases

Progeroid syndromes are rare genetic disorders that phenotypically resemble natural aging. Different causal mutations have been identified, but no molecular alterations have been identified that are in common to these diseases. DNA replication timing (RT) is a robust cell type-specific epigenetic fe...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Rivera-Mulia, Juan Carlos, Desprat, Romain, Trevilla-Garcia, Claudia, Cornacchia, Daniela, Schwerer, Hélène, Sasaki, Takayo, Sima, Jiao, Fells, Tyler, Studer, Lorenz, Lemaitre, Jean-Marc, Gilbert, David M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754778/
https://ncbi.nlm.nih.gov/pubmed/29196523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711613114
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares