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Replicating Large Genomes: Divide and Conquer

Complete duplication of large metazoan chromosomes requires thousands of potential initiation sites, only a small fraction of which are selected in each cell. Assembly of the replication machinery is highly conserved and tightly regulated during cell cycle, but the sites of initiation are highly fle...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Rivera-Mulia, Juan Carlos, Gilbert, David M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893193/
https://ncbi.nlm.nih.gov/pubmed/27259206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.007
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