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Replicating Large Genomes: Divide and Conquer

Complete duplication of large metazoan chromosomes requires thousands of potential initiation sites, only a small fraction of which are selected in each cell. Assembly of the replication machinery is highly conserved and tightly regulated during cell cycle, but the sites of initiation are highly fle...

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Publicado en:Mol Cell
Autores principales: Rivera-Mulia, Juan Carlos, Gilbert, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893193/
https://ncbi.nlm.nih.gov/pubmed/27259206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.007
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