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Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening

Protein-protein interactions (PPIs) represent important and promising therapeutic targets that are associated with the regulation of various molecular pathways, particularly in cancer. Although they were once considered “undruggable,” the recent advances in screening strategies, structure-based desi...

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書目詳細資料
發表在:Sci Rep
Main Authors: Mady, Ahmed S. A., Liao, Chenzhong, Bajwa, Naval, Kump, Karson J., Abulwerdi, Fardokht A., Lev, Katherine L., Miao, Lei, Grigsby, Sierrah M., Perdih, Andrej, Stuckey, Jeanne A., Du, Yuhong, Fu, Haian, Nikolovska-Coleska, Zaneta
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033896/
https://ncbi.nlm.nih.gov/pubmed/29976942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27899-9
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