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Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening
Protein-protein interactions (PPIs) represent important and promising therapeutic targets that are associated with the regulation of various molecular pathways, particularly in cancer. Although they were once considered “undruggable,” the recent advances in screening strategies, structure-based desi...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033896/ https://ncbi.nlm.nih.gov/pubmed/29976942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27899-9 |
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