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Atomic structures of corkscrew‐forming segments of SOD1 reveal varied oligomer conformations
The aggregation cascade of disease‐related amyloidogenic proteins, terminating in insoluble amyloid fibrils, involves intermediate oligomeric states. The structural and biochemical details of these oligomers have been largely unknown. Here we report crystal structures of variants of the cytotoxic ol...
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| Udgivet i: | Protein Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6032342/ https://ncbi.nlm.nih.gov/pubmed/29453800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3391 |
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