Atomic View of a Toxic Amyloid Small Oligomer

Amyloid diseases, including Alzheimer's, Parkinson's, and the prion conditions, are each associated with a particular protein in fibrillar form. These amyloid fibrils were long suspected to be the disease agents, but evidence suggests that smaller, often transient and polymorphic oligomers...

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Detalhes bibliográficos
Main Authors: Laganowsky, Arthur, Liu, Cong, Sawaya, Michael R., Whitelegge, Julian P., Park, Jiyong, Zhao, Minglei, Pensalfini, Anna, Soriaga, Angela, Landau, Meytal, Teng, Poh K., Cascio, Duilio, Glabe, Charles, Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959867/
https://ncbi.nlm.nih.gov/pubmed/22403391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1213151
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