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Toxic fibrillar oligomers of amyloid-β have cross-β structure
Although amyloid fibers are found in neurodegenerative diseases, evidence points to soluble oligomers of amyloid-forming proteins as the cytotoxic species. Here, we establish that our preparation of toxic amyloid-β(1–42) (Abeta42) fibrillar oligomers (TABFOs) shares with mature amyloid fibrils the c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356606/ https://ncbi.nlm.nih.gov/pubmed/22547798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203193109 |
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