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Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics

Protein amyloid oligomers have been strongly linked to amyloid diseases and can be intermediates to amyloid fibers. β-Sheets have been identified in amyloid oligomers. However, because of their transient and highly polymorphic properties, the details of their self-association remain elusive. Here we...

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Autors principals: Liu, Cong, Sawaya, Michael R., Cheng, Pin-Nan, Zheng, Jing, Nowick, James S., Eisenberg, David
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124511/
https://ncbi.nlm.nih.gov/pubmed/21473620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200222n
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