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Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity

The amyloid protein aggregation associated with diseases such as Alzheimer’s, Parkinson’s, and type II diabetes (among many others), features a bewildering variety of β-sheet-rich structures in transition from native proteins to ordered oligomers and fibers. The variation in the amino acid sequences...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Pin-Nan, Liu, Cong, Zhao, Minglei, Eisenberg, David, Nowick, James S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481199/
https://ncbi.nlm.nih.gov/pubmed/23089868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1433
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