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TG2 regulates the heat‐shock response by the post‐translational modification of HSF1

Heat‐shock factor 1 (HSF1) is the master transcription factor that regulates the response to proteotoxic stress by controlling the transcription of many stress‐responsive genes including the heat‐shock proteins. Here, we show a novel molecular mechanism controlling the activation of HSF1. We demonst...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Rossin, Federica, Villella, Valeria Rachela, D'Eletto, Manuela, Farrace, Maria Grazia, Esposito, Speranza, Ferrari, Eleonora, Monzani, Romina, Occhigrossi, Luca, Pagliarini, Vittoria, Sette, Claudio, Cozza, Giorgio, Barlev, Nikolai A, Falasca, Laura, Fimia, Gian Maria, Kroemer, Guido, Raia, Valeria, Maiuri, Luigi, Piacentini, Mauro
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030705/
https://ncbi.nlm.nih.gov/pubmed/29752334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745067
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