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Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

Cystic fibrosis (CF) patients harboring the most common deletion mutation of the CF transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset of CF patients who genetically carry plasma membrane (PM)-re...

詳細記述

保存先:
書誌詳細
主要な著者: Villella, Valeria Rachela, Esposito, Speranza, Bruscia, Emanuela M., Maiuri, Maria Chiara, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549520/
https://ncbi.nlm.nih.gov/pubmed/23346057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00001
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