Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

Cystic fibrosis (CF) patients harboring the most common deletion mutation of the CF transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset of CF patients who genetically carry plasma membrane (PM)-re...

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Detalhes bibliográficos
Main Authors: Villella, Valeria Rachela, Esposito, Speranza, Bruscia, Emanuela M., Maiuri, Maria Chiara, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549520/
https://ncbi.nlm.nih.gov/pubmed/23346057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00001
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