Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

Cystic fibrosis (CF) patients harboring the most common deletion mutation of the CF transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset of CF patients who genetically carry plasma membrane (PM)-re...

Full description

Saved in:
Bibliographic Details
Main Authors: Villella, Valeria Rachela, Esposito, Speranza, Bruscia, Emanuela M., Maiuri, Maria Chiara, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549520/
https://ncbi.nlm.nih.gov/pubmed/23346057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items