Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease

Cystic Fibrosis (CF) is the most frequent lethal monogenetic disease affecting humans. CF is characterized by mutations in cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel whose malfunction triggers the activation of transglutaminase-2 (TGM2), as well as the inactivatio...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Maiuri, Luigi, Raia, Valeria, Piacentini, Mauro, Tosco, Antonella, Villella, Valeria Rachela, Kroemer, Guido
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633896/
https://ncbi.nlm.nih.gov/pubmed/31321000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27037
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