Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease

In celiac disease (CD), an intolerance to dietary gluten/gliadin, antigenic gliadin peptides trigger an HLA-DQ2/DQ8-restricted adaptive Th1 immune response. Epithelial stress, induced by other non-antigenic gliadin peptides, is required for gliadin to become fully immunogenic. We found that cystic-f...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Esposito, Speranza, Villella, Valeria Rachela, Ferrari, Eleonora, Monzani, Romina, Tosco, Antonella, Rossin, Federica, D’Eletto, Manuela, Castaldo, Alice, Luciani, Alessandro, Silano, Marco, Bona, Gianni, Marseglia, Gian Luigi, Romani, Luigina, Piacentini, Mauro, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503870/
https://ncbi.nlm.nih.gov/pubmed/30981209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101888
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