Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation

Cystic fibrosis (CF), the most common lethal monogenic disease in Caucasians, is characterized by recurrent bacterial infections and colonization, mainly by Pseudomonas aeruginosa, resulting in unresolved airway inflammation. CF is caused by mutations in the gene coding for the cystic fibrosis trans...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ferrari, Eleonora, Monzani, Romina, Villella, Valeria R, Esposito, Speranza, Saluzzo, Francesca, Rossin, Federica, D'Eletto, Manuela, Tosco, Antonella, De Gregorio, Fabiola, Izzo, Valentina, Maiuri, Maria C, Kroemer, Guido, Raia, Valeria, Maiuri, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386380/
https://ncbi.nlm.nih.gov/pubmed/28079883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.476
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