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TG2 regulates the heat‐shock response by the post‐translational modification of HSF1

Heat‐shock factor 1 (HSF1) is the master transcription factor that regulates the response to proteotoxic stress by controlling the transcription of many stress‐responsive genes including the heat‐shock proteins. Here, we show a novel molecular mechanism controlling the activation of HSF1. We demonst...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Rossin, Federica, Villella, Valeria Rachela, D'Eletto, Manuela, Farrace, Maria Grazia, Esposito, Speranza, Ferrari, Eleonora, Monzani, Romina, Occhigrossi, Luca, Pagliarini, Vittoria, Sette, Claudio, Cozza, Giorgio, Barlev, Nikolai A, Falasca, Laura, Fimia, Gian Maria, Kroemer, Guido, Raia, Valeria, Maiuri, Luigi, Piacentini, Mauro
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030705/
https://ncbi.nlm.nih.gov/pubmed/29752334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745067
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