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Mechanism of vaccinia viral protein B14–mediated inhibition of IκB kinase β activation
Activation of IκB kinase β (IKKβ) is a central event in the NF-κB–mediated canonical pro-inflammatory pathway. Numerous studies have reported that oligomerization-mediated trans autophosphorylation of IKKβ is indispensable for its phosphorylation, leading to its activation and IKKβ-mediated phosphor...
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| Gepubliceerd in: | J Biol Chem |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028965/ https://ncbi.nlm.nih.gov/pubmed/29748387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002817 |
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