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Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

The IκB kinase (IKK) complex is a key regulator of signal transduction pathways leading to the induction of NF-κB-dependent gene expression and production of pro-inflammatory cytokines. It therefore represents a major target for the development of anti-inflammatory therapeutic drugs and may be targe...

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Библиографические подробности
Главные авторы: Chen, Ron A.-J, Ryzhakov, Grigory, Cooray, Samantha, Randow, Felix, Smith, Geoffrey L
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233672/
https://ncbi.nlm.nih.gov/pubmed/18266467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040022
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