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Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence

Vaccinia virus (VACV) strain Western Reserve protein C4 has been characterized and its function and contribution to virus virulence assessed. Bioinformatic analysis showed that C4 is conserved in six orthopoxvirus species and shares 43 % amino acid identity with VACV protein C16, a known virulence f...

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Bibliografische gegevens
Hoofdauteurs: Ember, Stuart W. J., Ren, Hongwei, Ferguson, Brian J., Smith, Geoffrey L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for General Microbiology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541790/
https://ncbi.nlm.nih.gov/pubmed/22791606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.045070-0
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