Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence

Vaccinia virus (VACV) expresses many proteins that are non-essential for virus replication but promote virulence by inhibiting components of the host immune response to infection. These immunomodulators include a family of proteins that have, or are predicted to have, a structure related to the B-ce...

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Detalhes bibliográficos
Principais autores: Ferguson, Brian J., Benfield, Camilla T. O., Ren, Hongwei, Lee, Vivian H., Frazer, Gordon L., Strnadova, Pavla, Sumner, Rebecca P., Smith, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2013
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749055/
https://ncbi.nlm.nih.gov/pubmed/23761407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.054114-0
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