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Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy

Vectors based on vaccinia virus (VACV), the vaccine used to eradicate smallpox, are currently popular candidates for the vaccination against numerous infectious diseases including malaria and AIDS. Although VACV induces robust cellular and humoral responses, enhancing the safety and efficacy of thes...

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書目詳細資料
Main Authors: Sumner, Rebecca P., Ren, Hongwei, Smith, Geoffrey L.
格式: Artigo
語言:Inglês
出版: Society for General Microbiology 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709586/
https://ncbi.nlm.nih.gov/pubmed/23288427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.049700-0
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