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Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy

Vectors based on vaccinia virus (VACV), the vaccine used to eradicate smallpox, are currently popular candidates for the vaccination against numerous infectious diseases including malaria and AIDS. Although VACV induces robust cellular and humoral responses, enhancing the safety and efficacy of thes...

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Autors principals: Sumner, Rebecca P., Ren, Hongwei, Smith, Geoffrey L.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709586/
https://ncbi.nlm.nih.gov/pubmed/23288427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.049700-0
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