First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity

Oncolytic viral therapy utilizes a tumor-selective replicating virus which preferentially infects and destroys cancer cells and triggers antitumor immunity. The Western Reserve strain of vaccinia virus (VV) is the most virulent strain of VV in animal models and has been engineered for tumor selectiv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther
Egile Nagusiak: Zeh, Herbert J, Downs-Canner, Stephanie, McCart, J Andrea, Guo, Zong Sheng, Rao, Uma N M, Ramalingam, Lekshmi, Thorne, Stephen H, Jones, Heather L, Kalinski, Pawel, Wieckowski, Eva, O'Malley, Mark E, Daneshmand, Manijeh, Hu, Kang, Bell, John C, Hwang, Tae-Ho, Moon, Anne, Breitbach, Caroline J, Kirn, David H, Bartlett, David L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426804/
https://ncbi.nlm.nih.gov/pubmed/25292189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.194
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