Oncolytic Virotherapy for Ovarian Carcinomatosis Using a Replication-Selective Vaccinia Virus Armed with a Yeast Cytosine Deaminase Gene

In this study, we assessed the ability of a highly tumor-selective oncolytic vaccinia virus armed with a yeast cytosine deaminase gene to infect and lyse human and murine ovarian tumors both in vitro and in vivo. The virus vvDD-CD could infect, replicate in and effectively lyse both human and mouse...

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書誌詳細
主要な著者: Chalikonda, Sricharan, Kivlen, Maryann H., O’Malley, Mark E., Dong, Xiang Da (Eric), McCart, J. Andrea, Gorry, Michael C., Yin, Xiao-Yu, Brown, Charles K., Zeh, Herbert J., Guo, Z. Sheng, Bartlett, David L.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975702/
https://ncbi.nlm.nih.gov/pubmed/18084242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cgt.7701110
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