Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers

BACKGROUND: Vaccinia viruses have emerged as attractive therapeutic candidates for cancer treatment due to their inherent ability of tumor tropism and oncolytic property. Cytosine deaminase (CD), which is derived from bacteria or yeast, can convert a relatively nontoxic prodrug 5-fluorocytosine (5-F...

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Detaylı Bibliyografya
Yayımlandı:Cancer Cell Int
Asıl Yazarlar: Ding, Yuedi, Fan, Jun, Deng, Lili, Huang, Biao, Zhou, Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296660/
https://ncbi.nlm.nih.gov/pubmed/32549790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01340-6
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