Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers

BACKGROUND: Vaccinia viruses have emerged as attractive therapeutic candidates for cancer treatment due to their inherent ability of tumor tropism and oncolytic property. Cytosine deaminase (CD), which is derived from bacteria or yeast, can convert a relatively nontoxic prodrug 5-fluorocytosine (5-F...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Cell Int
Main Authors: Ding, Yuedi, Fan, Jun, Deng, Lili, Huang, Biao, Zhou, Bin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Primary Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296660/
https://ncbi.nlm.nih.gov/pubmed/32549790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01340-6
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki