Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers

We have conducted a phase 1 study of intravenous vvDD, a Western Reserve strain oncolytic vaccinia virus, on 11 patients with standard treatment-refractory advanced colorectal or other solid cancers. The primary endpoints were maximum tolerated dose and associated toxicity while secondary endpoints...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Downs-Canner, Stephanie, Guo, Zong Sheng, Ravindranathan, Roshni, Breitbach, Caroline J, O'Malley, Mark E, Jones, Heather L, Moon, Anne, McCart, Judith Andrea, Shuai, Yongli, Zeh, Herbert J, Bartlett, David L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023393/
https://ncbi.nlm.nih.gov/pubmed/27203445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.101
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