Rapid Generation of Multiple Loci-Engineered Marker-free Poxvirus and Characterization of a Clinical-Grade Oncolytic Vaccinia Virus

Recombinant poxviruses, utilized as vaccine vectors and oncolytic viruses, often require manipulation at multiple genetic loci in the viral genome. It is essential for viral vectors to possess no adventitious mutations and no (antibiotic) selection marker in the final product for human patients in o...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Guo, Zong Sheng, Liu, Zuqiang, Sathaiah, Magesh, Wang, Jiahu, Ravindranathan, Roshni, Kim, Eun, Huang, Shaohua, Kenniston, Thomas W., Bell, John C., Zeh, Herbert J., Butterfield, Lisa H., Gambotto, Andrea, Bartlett, David L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651493/
https://ncbi.nlm.nih.gov/pubmed/29085848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.09.007
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