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Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14
The IκB kinase (IKK) complex is a key regulator of signal transduction pathways leading to the induction of NF-κB-dependent gene expression and production of pro-inflammatory cytokines. It therefore represents a major target for the development of anti-inflammatory therapeutic drugs and may be targe...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2233672/ https://ncbi.nlm.nih.gov/pubmed/18266467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040022 |
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