MEKK1 activates both IκB kinase α and IκB kinase β
A critical step in the signal-induced activation of the transcription factor NF-κB is the site-specific phosphorylation of its inhibitor, IκB, that targets the latter for degradation by the ubiquitin–proteasome pathway. We have previously shown that mitogen-activated protein kinase/ERK kinase kinase...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9319 |
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