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GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts
The Warburg effect is a predominant metabolic pathway in cancer cells characterized by enhanced glucose uptake and its conversion to L-lactate and is associated with upregulated expression of HIF-1α and activation of the EGFR-MEK-ERK, Wnt-β-catenin and PI3K-AKT signaling pathways. (R,R’)-4’-methoxy-...
Shranjeno v:
| izdano v: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028007/ https://ncbi.nlm.nih.gov/pubmed/28741686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30904 |
| Oznake: |
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