Activation of β2-adrenergic receptor by (R,R’)-4’-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells

(R,R’)-4’-methoxy-1-naphthylfenoterol [(R,R’)-MNF] is a highly-selective β(2) adrenergic receptor (β(2)-AR) agonist. Incubation of a panel of human-derived melanoma cell lines with (R,R’)-MNF resulted in a dose- and time-dependent inhibition of motility as assessed by in vitro wound healing and xCEL...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Wnorowski, Artur, Sadowska, Mariola, Paul, Rajib K., Singh, Nagendra S., Boguszewska-Czubara, Anna, Jimenez, Lucita, Abdelmohsen, Kotb, Toll, Lawrence, Jozwiak, Krzysztof, Bernier, Michel, Wainer, Irving W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361792/
https://ncbi.nlm.nih.gov/pubmed/25703025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.02.012
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