(R,R′)-4′-Methoxy-1-naphthylfenoterol Targets GPR55-mediated Ligand Internalization and Impairs Cancer Cell Motility

(R,R′)-4′-Methoxy-1-naphthylfenoterol (MNF) promotes growth inhibition and apoptosis of human HepG2 hepatocarcinoma cells via cannabinoid receptor (CBR) activation. The synthetic CB(1)R inverse agonist, AM251, has been shown to block the anti-mitogenic effect of MNF in these cells; however, AM251 is...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Paul, Rajib K., Wnorowski, Artur, Gonzalez-Mariscal, Isabel, Nayak, Surendra K., Pajak, Karolina, Moaddel, Ruin, Indig, Fred E., Bernier, Michel, Wainer, Irving W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935314/
https://ncbi.nlm.nih.gov/pubmed/24355564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.11.020
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky