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Selective GPR55 antagonism reduces chemoresistance in cancer cells
G protein-coupled receptor 55 (GPR55) possesses pro-oncogenic activity and its function can be competitively inhibited with (R,R’)-4’-methoxy-1-naphthylfenoterol (MNF) through poorly defined signaling pathways. Here, the anti-tumorigenic effect of MNF was investigated in the human pancreatic cancer...
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| Veröffentlicht in: | Pharmacol Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026616/ https://ncbi.nlm.nih.gov/pubmed/27423937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.07.013 |
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