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The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells
Chemoresistance of cancer cells has been a severe problem in multiple types of cancers. One possibility is to combine different drugs with chemotherapy for improved efficacy. Cyclopamine blocks Hedgehog signaling by antagonizing Smo function, which induces tumor apoptosis. Here, we show that the com...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829677/ https://ncbi.nlm.nih.gov/pubmed/24250231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S51914 |
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