Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor
Exposure to cyclopamine, a steroid alkaloid that blocks Sonic hedgehog (Shh) signaling, promotes pancreatic expansion in embryonic chicks. Heterotopic development of pancreatic endocrine and exocrine structures occurs in regions adjacent to the pancreas including stomach and duodenum, and insulin-pr...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13036 |
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